Vaccine "unnaturalness" (artificiality) is one of the major anti-vaccine arguments raised in public debate. Therefore. health communication should rebut unnaturalness arguments and be cautious when emphasizing human intervention (e. g. https://www.ngetikin.com/limited-value-Sapatilha-Infantil-Pampili-Bailarina-Laco-Duplo-Glitter-Prata-great-pick/